The House of Wise Men is the oldest of the houses of Alchemy, specializing in rituals to try and bring forth the creator. They produce a massive portion of essential products for high-ranking wizards
The goods they manufacture include the drugs that allow for the performance of more intense spells. Otherwise, they perform rituals that involve the use of the human body as a transmutation grid through which eternal life can be extracted, however, they have yet to complete one of these rituals properly, only bringing what they believe to be the creator closer to entering our reality. The founder, Wiseman, rarely communicates directly with his followers but has been confirmed to still be living somehow.